D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain.
Identifieur interne : 000489 ( Main/Exploration ); précédent : 000488; suivant : 000490D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain.
Auteurs : Andrés Ant N [Espagne] ; María Angeles Marcos ; Miguel Julián Martínez ; Susana Ram N ; Anna Martínez ; Neus Carde Osa ; Pere Godoy ; Nuria Torner ; Patricia De Molina ; Ricard Isanta ; María Teresa Jiménez De Anta ; Tomàs PumarolaSource :
- Diagnostic microbiology and infectious disease [ 1879-0070 ] ; 2010.
Descripteurs français
- KwdFr :
- Analyse de séquence d'ADN (MeSH), Espagne (MeSH), Grippe humaine (virologie), Humains (MeSH), Hémagglutinines virales (génétique), Hémagglutinines virales (isolement et purification), Mutation faux-sens (MeSH), Mutation ponctuelle (MeSH), Sous-type H1N1 du virus de la grippe A (génétique), Sous-type H1N1 du virus de la grippe A (isolement et purification).
- MESH :
- génétique : Hémagglutinines virales, Sous-type H1N1 du virus de la grippe A.
- isolement et purification : Hémagglutinines virales, Sous-type H1N1 du virus de la grippe A.
- virologie : Grippe humaine.
- Analyse de séquence d'ADN, Espagne, Humains, Mutation faux-sens, Mutation ponctuelle.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- Hemagglutinins, Viral (genetics), Hemagglutinins, Viral (isolation & purification), Humans (MeSH), Influenza A Virus, H1N1 Subtype (genetics), Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza, Human (virology), Mutation, Missense (MeSH), Point Mutation (MeSH), Sequence Analysis, DNA (MeSH), Spain (MeSH).
- MESH :
- chemical , genetics : Hemagglutinins, Viral.
- chemical , isolation & purification : Hemagglutinins, Viral.
- geographic : Spain.
- genetics : Influenza A Virus, H1N1 Subtype.
- isolation & purification : Influenza A Virus, H1N1 Subtype.
- virology : Influenza, Human.
- Humans, Mutation, Missense, Point Mutation, Sequence Analysis, DNA.
Abstract
From 27 April to 16 December 2009, we analyzed the hemagglutinin gene sequence of 2009 pandemic influenza A (H1N1) virus in 189 respiratory specimens. We only found the D225G mutation in 3 severe cases. However, it was not found in samples from other cases with or without clinical criteria of severity. The biologic significance of this mutation remains still unclear.
DOI: 10.1016/j.diagmicrobio.2010.02.002
PubMed: 20356695
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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uniqKey="Isanta R" first="Ricard" last="Isanta">Ricard Isanta</name></author><author><name sortKey="Jimenez De Anta, Maria Teresa" sort="Jimenez De Anta, Maria Teresa" uniqKey="Jimenez De Anta M" first="María Teresa" last="Jiménez De Anta">María Teresa Jiménez De Anta</name></author><author><name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomàs" last="Pumarola">Tomàs Pumarola</name></author></analytic><series><title level="j">Diagnostic microbiology and infectious disease</title><idno type="eISSN">1879-0070</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hemagglutinins, Viral (genetics)</term><term>Hemagglutinins, Viral (isolation & purification)</term><term>Humans (MeSH)</term><term>Influenza A Virus, H1N1 Subtype (genetics)</term><term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term><term>Influenza, Human (virology)</term><term>Mutation, Missense (MeSH)</term><term>Point Mutation (MeSH)</term><term>Sequence Analysis, DNA (MeSH)</term><term>Spain (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de séquence d'ADN (MeSH)</term><term>Espagne (MeSH)</term><term>Grippe humaine (virologie)</term><term>Humains (MeSH)</term><term>Hémagglutinines virales (génétique)</term><term>Hémagglutinines virales (isolement et purification)</term><term>Mutation faux-sens (MeSH)</term><term>Mutation ponctuelle (MeSH)</term><term>Sous-type H1N1 du virus de la grippe A (génétique)</term><term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Hemagglutinins, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Hemagglutinins, Viral</term></keywords><keywords 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DNA</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de séquence d'ADN</term><term>Espagne</term><term>Humains</term><term>Mutation faux-sens</term><term>Mutation ponctuelle</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">From 27 April to 16 December 2009, we analyzed the hemagglutinin gene sequence of 2009 pandemic influenza A (H1N1) virus in 189 respiratory specimens. We only found the D225G mutation in 3 severe cases. However, it was not found in samples from other cases with or without clinical criteria of severity. The biologic significance of this mutation remains still unclear.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20356695</PMID><DateCompleted><Year>2010</Year><Month>08</Month><Day>09</Day></DateCompleted><DateRevised><Year>2010</Year><Month>09</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1879-0070</ISSN><JournalIssue CitedMedium="Internet"><Volume>67</Volume><Issue>2</Issue><PubDate><Year>2010</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Diagnostic microbiology and infectious disease</Title><ISOAbbreviation>Diagn. Microbiol. Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain.</ArticleTitle><Pagination><MedlinePgn>207-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.diagmicrobio.2010.02.002</ELocationID><Abstract><AbstractText>From 27 April to 16 December 2009, we analyzed the hemagglutinin gene sequence of 2009 pandemic influenza A (H1N1) virus in 189 respiratory specimens. We only found the D225G mutation in 3 severe cases. However, it was not found in samples from other cases with or without clinical criteria of severity. The biologic significance of this mutation remains still unclear.</AbstractText><CopyrightInformation>Copyright 2010 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Antón</LastName><ForeName>Andrés</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Microbiology Laboratory, Hospital Clínic, 08036 Barcelona, Spain. aanton76@gmail.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marcos</LastName><ForeName>María Angeles</ForeName><Initials>MA</Initials></Author><Author ValidYN="Y"><LastName>Martínez</LastName><ForeName>Miguel Julián</ForeName><Initials>MJ</Initials></Author><Author ValidYN="Y"><LastName>Ramón</LastName><ForeName>Susana</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Martínez</LastName><ForeName>Anna</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Cardeñosa</LastName><ForeName>Neus</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Godoy</LastName><ForeName>Pere</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Torner</LastName><ForeName>Nuria</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>De Molina</LastName><ForeName>Patricia</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Isanta</LastName><ForeName>Ricard</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Jiménez de Anta</LastName><ForeName>María Teresa</ForeName><Initials>MT</Initials></Author><Author ValidYN="Y"><LastName>Pumarola</LastName><ForeName>Tomàs</ForeName><Initials>T</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2010</Year><Month>03</Month><Day>31</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Diagn Microbiol Infect 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MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020125" MajorTopicYN="Y">Mutation, Missense</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017354" MajorTopicYN="Y">Point Mutation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017422" MajorTopicYN="N">Sequence Analysis, DNA</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2010</Year><Month>01</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2010</Year><Month>02</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>4</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>4</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>8</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">20356695</ArticleId><ArticleId IdType="pii">S0732-8893(10)00038-6</ArticleId><ArticleId IdType="doi">10.1016/j.diagmicrobio.2010.02.002</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Espagne</li></country><region><li>Catalogne</li></region></list><tree><noCountry><name sortKey="Carde Osa, Neus" sort="Carde Osa, Neus" uniqKey="Carde Osa N" first="Neus" last="Carde Osa">Neus Carde Osa</name><name sortKey="De Molina, Patricia" sort="De Molina, Patricia" uniqKey="De Molina P" first="Patricia" last="De Molina">Patricia De Molina</name><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name><name sortKey="Isanta, Ricard" sort="Isanta, Ricard" uniqKey="Isanta R" first="Ricard" last="Isanta">Ricard Isanta</name><name sortKey="Jimenez De Anta, Maria Teresa" sort="Jimenez De Anta, Maria Teresa" uniqKey="Jimenez De Anta M" first="María Teresa" last="Jiménez De Anta">María Teresa Jiménez De Anta</name><name sortKey="Marcos, Maria Angeles" sort="Marcos, Maria Angeles" uniqKey="Marcos M" first="María Angeles" last="Marcos">María Angeles Marcos</name><name sortKey="Martinez, Anna" sort="Martinez, Anna" uniqKey="Martinez A" first="Anna" last="Martínez">Anna Martínez</name><name sortKey="Martinez, Miguel Julian" sort="Martinez, Miguel Julian" uniqKey="Martinez M" first="Miguel Julián" last="Martínez">Miguel Julián Martínez</name><name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomàs" last="Pumarola">Tomàs Pumarola</name><name sortKey="Ram N, Susana" sort="Ram N, Susana" uniqKey="Ram N S" first="Susana" last="Ram N">Susana Ram N</name><name sortKey="Torner, Nuria" sort="Torner, Nuria" uniqKey="Torner N" first="Nuria" last="Torner">Nuria Torner</name></noCountry><country name="Espagne"><region name="Catalogne"><name sortKey="Ant N, Andres" sort="Ant N, Andres" uniqKey="Ant N A" first="Andrés" last="Ant N">Andrés Ant N</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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